2PI6
Crystal structure of the sheep signalling glycoprotein (SPS-40) complex with 2-methyl-2-4-pentanediol at 1.65A resolution reveals specific binding characteristics of SPS-40
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Chitinase-3-like protein 1 | polymer | 361 | 40757.0 | 1 | UniProt (Q6TMG6) Pfam (PF00704) In PDB | Ovis aries (sheep) | Signal-processing protein, Secretory glyoprotein of 40 kDa |
| 2 | B | alpha-D-mannopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42402GU) | |||
| 3 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 4 | A | ETHANOL | non-polymer | 46.1 | 3 | Chemie (EOH) | |||
| 5 | water | water | 18.0 | 586 | Chemie (HOH) |
Sequence modifications
A: 1 - 362 (UniProt: Q6TMG6)
| PDB | External Database | Details |
|---|---|---|
| Thr 36 | Ser 36 | SEE REMARK 999 |
| Lys 87 | Ala 87 | SEE REMARK 999 |
| Arg 203 | Ala 203 | SEE REMARK 999 |
| Ile 262 | Val 261 | SEE REMARK 999 |
| Ala 362 | Val 361 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40757.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 910.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 374.6 | |
| All* | Total formula weight | 42042.4 |
