2PI2

Full-length Replication protein A subunits RPA14 and RPA32

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Replication protein A 32 kDa subunit	polymer	270	29276.8	4	UniProt (P15927) Pfam (PF08784)	Homo sapiens (human)	RP-A, RF-A, Replication factor-A protein 2, p32, p34
2	E, F, G, H (E, F, G, H)	Replication protein A 14 kDa subunit	polymer	142	16117.5	4	UniProt (P35244) Pfam (PF08661)	Homo sapiens (human)	RP-A, RF-A, Replication factor-A protein 3, p14
3	I, J, K, L (A, B, C, D)	1,4-DIETHYLENE DIOXIDE	non-polymer		88.1	4	Chemie (DIO)
4	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	244	Chemie (HOH)

Sequence modifications

E, F, G, H: 1 - 121 (UniProt: P35244)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	181577.0
Non-Polymers*	Number of molecules	4
	Total formula weight	352.4
All*	Total formula weight	181929.4

*Water molecules are not included.