2PGZ
Crystal structure of Cocaine bound to an ACh-Binding Protein
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Soluble acetylcholine receptor | polymer | 230 | 26212.1 | 5 | UniProt (Q8WSF8) Pfam (PF02931) In PDB | Aplysia californica (California sea hare) | |
2 | F | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
3 | A, D | COCAINE | non-polymer | 303.4 | 2 | Chemie (COC) | |||
4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
5 | B, C, E | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
6 | water | water | 18.0 | 1141 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 219 (UniProt: Q8WSF8)
PDB | External Database | Details |
---|---|---|
Asp -8 | - | cloning artifact |
Tyr -7 | - | cloning artifact |
Lys -6 | - | cloning artifact |
Asp -5 | - | cloning artifact |
Asp -4 | - | cloning artifact |
Asp -3 | - | cloning artifact |
Asp -2 | - | cloning artifact |
Lys -1 | - | cloning artifact |
Leu 0 | - | cloning artifact |
Ser 220 | - | cloning artifact |
Arg 221 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 131060.5 | |
Branched | Number of molecules | 1 |
Total formula weight | 910.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1410.6 | |
All* | Total formula weight | 133381.9 |