2PBW
Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex with the Partial agonist Domoic Acid at 2.5 A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor, ionotropic kainate 1 | polymer | 257 | 29108.5 | 2 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | Glutamate receptor 5, GluR-5, GluR5 |
| 2 | C, D (A, B) | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID | non-polymer | 311.3 | 2 | Chemie (DOQ) PubChem (3150) PubChem (100314) PubChem (5282253) PubChem (5311075) PubChem (5792610) PubChem (6426712) PubChem (6442551) PubChem (6446300) PubChem (10380744) PubChem (17753955) PubChem (23428218) PubChem (23428220) PubChem (23428300) PubChem (24066939) PubChem (44568340) PubChem (23428219) PubChem (54601877) PubChem (6604708) PubChem (57156195) PubChem (57367983) PubChem (71308186) PubChem (101705185) PubChem (101762098) PubChem (101790920) PubChem (131632567) PubChem (133124932) PubChem (162916709) PubChem (162916710) PubChem (162916711) PubChem (162916712) PubChem (162916713) PubChem (172834624) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 116 (UniProt: P22756)
A, B: 119 - 257 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Gly 34 | Ala 477 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58216.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 622.7 | |
| All* | Total formula weight | 58839.6 |
