2PBW
Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex with the Partial agonist Domoic Acid at 2.5 A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor, ionotropic kainate 1 | polymer | 257 | 29108.5 | 2 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | Glutamate receptor 5, GluR-5, GluR5 |
| 2 | C, D (A, B) | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID | non-polymer | 311.3 | 2 | Chemie (DOQ) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 116 (UniProt: P22756)
A, B: 119 - 257 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Gly 34 | Ala 477 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58216.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 622.7 | |
| All* | Total formula weight | 58839.6 |
