2PA5
Crystal structure of human protein tyrosine phosphatase PTPN9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein phosphatase non-receptor type 9 | polymer | 314 | 36229.1 | 2 | UniProt (P43378) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase MEG2, PTPase-MEG2 |
| 2 | C, D, E, I (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 3 | F (A) | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 4 | G, H, J, K, L (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 405 | Chemie (HOH) |
Sequence modifications
A, B: 277 - 582 (UniProt: P43378)
| PDB | External Database | Details |
|---|---|---|
| Met 276 | - | cloning artifact |
| Ala 583 | - | cloning artifact |
| His 584 | - | cloning artifact |
| His 585 | - | cloning artifact |
| His 586 | - | cloning artifact |
| His 587 | - | cloning artifact |
| His 588 | - | cloning artifact |
| His 589 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72458.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 510.2 | |
| All* | Total formula weight | 72968.3 |
