Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 591 |
| Chain | Residue |
| A | THR402 |
| A | LYS411 |
| A | SER516 |
| A | HOH761 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 590 |
| Chain | Residue |
| B | ARG332 |
| B | ARG410 |
| B | HOH764 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 592 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SCN A 601 |
| Chain | Residue |
| A | ILE481 |
| A | PHE574 |
| A | LYS577 |
| A | HOH750 |
| A | HOH919 |
| A | ALA478 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 701 |
| Chain | Residue |
| A | SER475 |
| B | ASP335 |
| B | ALA517 |
| B | GLN559 |
| B | HOH733 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 702 |
| Chain | Residue |
| B | GLY365 |
| B | TYR366 |
| B | GLN368 |
| B | ALA371 |
| B | TYR372 |
| B | ASP529 |
| B | ILE530 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 703 |
| Chain | Residue |
| A | GLN289 |
| A | ARG425 |
| A | GLY427 |
| A | MET580 |
| A | VAL581 |
| A | SER582 |
| A | HOH921 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 704 |
| Chain | Residue |
| A | PRO474 |
| A | SER475 |
| A | PHE566 |
| A | LYS569 |
| A | ALA570 |
| A | GLU573 |
| A | HOH809 |
| A | HOH845 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 705 |
| Chain | Residue |
| A | LEU466 |
| B | ARG312 |
| B | HOH771 |
| B | HOH786 |
| B | HOH823 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
| Chain | Residue | Details |
| A | VAL513-GLY523 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10044","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | ARG521 | |
| A | HIS514 | |
| A | GLU406 | |
| A | THR522 | |
| A | CYS515 | |
| A | ASP470 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | ARG521 | |
| B | GLU406 | |
| B | HIS514 | |
| B | CYS515 | |
| B | THR522 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | ARG521 | |
| A | ASP470 | |
| A | THR522 | |
| A | CYS515 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | ARG521 | |
| B | THR522 | |
| B | CYS515 | |
