Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0016311 | biological_process | dephosphorylation |
B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
B | 0006470 | biological_process | protein dephosphorylation |
B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 591 |
Chain | Residue |
A | THR402 |
A | LYS411 |
A | SER516 |
A | HOH761 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 590 |
Chain | Residue |
B | ARG332 |
B | ARG410 |
B | HOH764 |
site_id | AC3 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL A 592 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SCN A 601 |
Chain | Residue |
A | ILE481 |
A | PHE574 |
A | LYS577 |
A | HOH750 |
A | HOH919 |
A | ALA478 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 701 |
Chain | Residue |
A | SER475 |
B | ASP335 |
B | ALA517 |
B | GLN559 |
B | HOH733 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 702 |
Chain | Residue |
B | GLY365 |
B | TYR366 |
B | GLN368 |
B | ALA371 |
B | TYR372 |
B | ASP529 |
B | ILE530 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO A 703 |
Chain | Residue |
A | GLN289 |
A | ARG425 |
A | GLY427 |
A | MET580 |
A | VAL581 |
A | SER582 |
A | HOH921 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO A 704 |
Chain | Residue |
A | PRO474 |
A | SER475 |
A | PHE566 |
A | LYS569 |
A | ALA570 |
A | GLU573 |
A | HOH809 |
A | HOH845 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 705 |
Chain | Residue |
A | LEU466 |
B | ARG312 |
B | HOH771 |
B | HOH786 |
B | HOH823 |
Functional Information from PROSITE/UniProt
site_id | PS00383 |
Number of Residues | 11 |
Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
Chain | Residue | Details |
A | VAL513-GLY523 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS515 | |
B | CYS515 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ASP470 | |
A | CYS515 | |
A | GLN559 | |
B | ASP470 | |
B | CYS515 | |
B | GLN559 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 6 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
A | ARG521 | |
A | HIS514 | |
A | GLU406 | |
A | THR522 | |
A | CYS515 | |
A | ASP470 | |
site_id | CSA2 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
B | ARG521 | |
B | GLU406 | |
B | HIS514 | |
B | CYS515 | |
B | THR522 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
A | ARG521 | |
A | ASP470 | |
A | THR522 | |
A | CYS515 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
B | ARG521 | |
B | THR522 | |
B | CYS515 | |