2P8E

Crystal structure of the serine/threonine phosphatase domain of human PPM1B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PPM1B beta isoform variant 6	polymer	307	34305.3	2	UniProt (Q4J6C0) Pfam (PF00481) UniProt (by SIFTS) (O75688)	Homo sapiens (human)	Protein phosphatase 2C isoform beta, PP2C-beta
2	C, D (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	E, F (A, B)	water	water		18.0	431	Chemie (HOH)

Sequence modifications

A, B: 2 - 297 (UniProt: Q4J6C0)

PDB	External Database	Details
Met -1	-	expression tag
Ser 0	-	expression tag
Leu 1	-	expression tag
Glu 298	-	expression tag
Gly 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68610.6
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	68659.2

*Water molecules are not included.