2P5N
Crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase in complex with coenzyme NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aldo-keto reductase family 1, member C21 | polymer | 323 | 36924.6 | 2 | UniProt (Q6P8V0) Pfam (PF00248) UniProt (by SIFTS) (Q91WR5) In PDB | Mus musculus (house mouse) | 17-alpha hydroxysteroid dehydrogenase, AKR1C21 |
| 2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | A, B | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 4 | water | water | 18.0 | 569 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 323 (UniProt: Q6P8V0)
| PDB | External Database | Details |
|---|---|---|
| Lys 294 | Glu 294 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73849.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1727.2 | |
| All* | Total formula weight | 75576.3 |
