2P5B
The complex structure of JMJD2A and trimethylated H3K36 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | JmjC domain-containing histone demethylation protein 3A | polymer | 352 | 40863.5 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (human) | Jumonji domain-containing protein 2A |
| 2 | C, D (I, J) | Histone H3 | polymer | 22 | 2425.9 | 2 | UniProt (P84239) | ||
| 3 | E, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, K (A, B) | FE (II) ION | non-polymer | 55.8 | 2 | Chemie (FE2) | |||
| 5 | G, L (A, B) | N-OXALYLGLYCINE | non-polymer | 147.1 | 2 | Chemie (OGA) | |||
| 6 | H, I, M (A, B) | OXYGEN MOLECULE | non-polymer | 32.0 | 3 | Chemie (OXY) | |||
| 7 | N, O, P, Q (A, B, I, J) | water | water | 18.0 | 284 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 350 (UniProt: O75164)
I, J: 0 - 20 (UniProt: P84239)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Met 1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| M3l 10 | Lys 37 | modified residue |
| Leu 21 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 86578.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 632.7 | |
| All* | Total formula weight | 87211.5 |
