2P59
Crystal Structure of Hepatitis C Virus NS3.4A protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NS3 | polymer | 181 | 19179.9 | 2 | UniProt (A1Z093) Pfam (PF02907) UniProt (by SIFTS) (Q91RS4) | Hepatitis C virus | |
| 2 | C, D (C, D) | peptide | polymer | 21 | 2077.6 | 2 | Pfam (PF01006) UniProt (by SIFTS) (P27958) | ||
| 3 | E (B) | (2S,3AS,7AS)-1-[(2S)-2-{[(2S)-2-CYCLOHEXYL-2-({[(2R)-4-NITRO-2H-PYRROL-2-YL]CARBONYL}AMINO)ACETYL]AMINO}-3,3-DIMETHYLBUTANOYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]BUTYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE | non-polymer | 727.9 | 1 | Chemie (GG4) |
Sequence modifications
A, B: 27 - 207 (UniProt: A1Z093)
| PDB | External Database | Details |
|---|---|---|
| Glu 202 | Gly 176 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42515.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 727.9 | |
| All* | Total formula weight | 43242.9 |
