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2P59

Crystal Structure of Hepatitis C Virus NS3.4A protease

Functional Information from GO Data
ChainGOidnamespacecontents
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0008236molecular_functionserine-type peptidase activity
A0016020cellular_componentmembrane
A0019062biological_processvirion attachment to host cell
A0019087biological_processtransformation of host cell by virus
A0033644cellular_componenthost cell membrane
A0044423cellular_componentvirion component
A0046718biological_processsymbiont entry into host cell
A0046872molecular_functionmetal ion binding
A0097264biological_processself proteolysis
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0008236molecular_functionserine-type peptidase activity
B0016020cellular_componentmembrane
B0019062biological_processvirion attachment to host cell
B0019087biological_processtransformation of host cell by virus
B0033644cellular_componenthost cell membrane
B0044423cellular_componentvirion component
B0046718biological_processsymbiont entry into host cell
B0046872molecular_functionmetal ion binding
B0097264biological_processself proteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE GG4 B 1208
ChainResidue
BGLN1067
BALA1183
BVAL1184
BCYS1185
BASP1194
BTHR1068
BHIS1083
BLYS1162
BGLY1163
BSER1164
BSER1165
BARG1181
BALA1182

Catalytic Information from CSA
site_idCSA1
Number of Residues4
DetailsAnnotated By Reference To The Literature 1rgq
ChainResidueDetails
AASP107
AHIS83
ASER165
AGLY163

site_idCSA2
Number of Residues4
DetailsAnnotated By Reference To The Literature 1rgq
ChainResidueDetails
BGLY1163
BASP1107
BHIS1083
BSER1165

site_idMCSA1
Number of Residues
DetailsM-CSA 776
ChainResidueDetails

site_idMCSA2
Number of Residues
DetailsM-CSA 776
ChainResidueDetails

222415

PDB entries from 2024-07-10

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