2P54
a crystal structure of PPAR alpha bound with SRC1 peptide and GW735
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor alpha | polymer | 267 | 30270.4 | 1 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens (human) | PPAR-alpha |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 12 | 1518.8 | 1 | UniProt (Q15788) | NCoA-1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal carcinoma antigen NY-REN-52 | |
| 3 | C (A) | 2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID | non-polymer | 478.5 | 1 | Chemie (735) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
B: 686 - 696 (UniProt: Q15788)
| PDB | External Database | Details |
|---|---|---|
| Ala 685 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31789.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 478.5 | |
| All* | Total formula weight | 32267.7 |
