2P4D
Structure-assisted discovery of Variola major H1 phosphatase inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity protein phosphatase | polymer | 172 | 20235.2 | 1 | UniProt (P33064) | Variola virus | Late protein H1 |
| 2 | B (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 1 - 171 (UniProt: P33064)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | cloning artifact |
| Mse 18 | Met 18 | modified residue |
| Mse 27 | Met 27 | modified residue |
| Mse 43 | Met 43 | modified residue |
| Mse 60 | Met 60 | modified residue |
| Mse 120 | Met 120 | modified residue |
| Mse 126 | Met 126 | modified residue |
| Mse 135 | Met 135 | modified residue |
| Mse 145 | Met 145 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20235.2 | |
| All* | Total formula weight | 20235.2 |
