2P3U
Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor X | polymer | 52 | 5589.2 | 1 | UniProt (P00742) Pfam (PF14670) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 2 | B (B) | Coagulation factor X | polymer | 233 | 26346.0 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 3 | C, D (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E (B) | 3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE | non-polymer | 550.8 | 1 | Chemie (663) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31935.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 631.0 | |
| All* | Total formula weight | 32566.2 |
