2P16
Factor Xa in Complex with the Inhibitor APIXABAN (BMS-562247) AKA 1-(4-METHOXYPHENYL)-7-OXO-6-(4-(2-OXO-1-PIPERIDINYL)PHENYL)-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3, 4-C]PYRIDINE-3-CARBOXAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) | polymer | 234 | 26447.1 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | FACTOR XA HEAVY CHAIN, ACTIVATED FACTOR XA HEAVY CHAIN |
| 2 | B (L) | Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) | polymer | 52 | 5589.2 | 1 | UniProt (P00742) Pfam (PF14670) | Homo sapiens (human) | FACTOR XA LIGHT CHAIN |
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (A) | 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDINE-3-CARBOXAMIDE | non-polymer | 459.5 | 1 | Chemie (GG2) | |||
| 5 | E, F (A, L) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32036.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 499.6 | |
| All* | Total formula weight | 32535.9 |
