2P0R
Structure of Human Calpain 9 in complex with Leupeptin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Calpain-9 | polymer | 333 | 37528.0 | 2 | UniProt (O14815) Pfam (PF00648) | Homo sapiens (human) | Digestive tract-specific calpain; nCL-4; CG36 protein |
| 2 | C, D (D, E) | leupeptin | polymer | 4 | 429.6 | 2 | NOR (NOR00487) BIRD (PRD_000216) | Actinomycetes Streptomyces roseus MA 839-A1 | |
| 3 | E, F, G, H, I (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | J, K (A, B) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 340 (UniProt: O14815)
| PDB | External Database | Details |
|---|---|---|
| Gly 8 | - | expression tag |
| Ser 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 75915.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 200.4 | |
| All* | Total formula weight | 76115.5 |
