2OW3

Glycogen synthase kinase-3 beta in complex with bis-(indole)maleimide pyridinophane inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycogen synthase kinase-3 beta	polymer	352	40082.0	2	UniProt (P49841) Pfam (PF00069)	Homo sapiens (human)	GSK-3 beta
2	C, D (A, B)	BIS-(INDOLE)MALEIMIDE PYRIDINOPHANE	non-polymer		543.7	2	Chemie (BIM)
3	E, F (A, B)	water	water		18.0	15	Chemie (HOH)

Sequence modifications

A, B: 35 - 386 (UniProt: P49841)

PDB	External Database	Details
Ptr 216	Tyr 216	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80164.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1087.3
All*	Total formula weight	81251.3

*Water molecules are not included.