2OVY
Crystal structure of the catalytic domain of rat phosphodiesterase 10A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphodiesterase-10A | polymer | 362 | 41661.7 | 1 | UniProt (Q9QYJ6) Pfam (PF00233) | Rattus norvegicus (Norway rat) | PDE10A2 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | 6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE | non-polymer | 403.4 | 1 | Chemie (PFJ) | |||
| 6 | F (A) | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence modifications
A: 442 - 784 (UniProt: Q9QYJ6)
| PDB | External Database | Details |
|---|---|---|
| Met 423 | - | expression tag |
| His 424 | - | expression tag |
| His 425 | - | expression tag |
| His 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
| His 429 | - | expression tag |
| Ser 430 | - | expression tag |
| Ser 431 | - | expression tag |
| Gly 432 | - | expression tag |
| Leu 433 | - | expression tag |
| Val 434 | - | expression tag |
| Pro 435 | - | expression tag |
| Arg 436 | - | expression tag |
| Gly 437 | - | expression tag |
| Ser 438 | - | expression tag |
| Ala 439 | - | expression tag |
| Met 440 | - | expression tag |
| Gly 441 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41661.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 589.2 | |
| All* | Total formula weight | 42250.9 |
