2OVR
Structure of the Skp1-Fbw7-CyclinEdegN complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | S-phase kinase-associated protein 1A | polymer | 149 | 16853.2 | 1 | UniProt (P63208) Pfam (PF03931) Pfam (PF01466) In PDB | Homo sapiens (human) | Skp1; Cyclin A/CDK2-associated protein p19; p19A; p19skp1; RNA polymerase II elongation factor-like protein; Organ of Corti protein 2; OCP-II protein; OCP-2; Transcription elongation factor B; SIII |
2 | B | F-box/WD repeat protein 7 | polymer | 445 | 50279.4 | 1 | UniProt (Q969H0) Pfam (PF00400) Pfam (PF12937) In PDB | Homo sapiens (human) | Fbw7; F-box and WD-40 domain protein 7; F-box protein FBX30; hCdc4; Archipelago homolog; hAgo; SEL-10 |
3 | C | cyclinE N-terminal degron | polymer | 8 | 951.0 | 1 | |||
4 | B | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
5 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A: 1001 - 1149 (UniProt: P63208)
PDB | External Database | Details |
---|---|---|
- | Asp 37 | deletion |
- | Asp 38 | deletion |
- | Glu 39 | deletion |
- | Gly 40 | deletion |
- | Asp 41 | deletion |
- | Asp 42 | deletion |
- | Pro 70 | deletion |
- | Pro 71 | deletion |
- | Pro 72 | deletion |
- | Glu 73 | deletion |
- | Asp 74 | deletion |
- | Asp 75 | deletion |
- | Glu 76 | deletion |
- | Asn 77 | deletion |
Gly 1078 | Lys 78 | linker |
Gly 1079 | Glu 79 | linker |
Ser 1080 | Lys 80 | linker |
Gly 1081 | Arg 81 | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 68083.6 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1152.8 | |
All* | Total formula weight | 69236.3 |