Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 901 |
| Chain | Residue |
| B | HOH83 |
| B | HOH143 |
| B | HOH196 |
| B | ARG2505 |
| B | ARG2674 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 902 |
| Chain | Residue |
| B | HOH46 |
| B | GLN2428 |
| B | ARG2676 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 903 |
| Chain | Residue |
| B | THR2416 |
| B | ARG2415 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 904 |
| Chain | Residue |
| B | HOH5 |
| B | HOH12 |
| B | HOH25 |
| B | HOH87 |
| B | GLN2618 |
| B | PRO2620 |
| B | GLU2655 |
| B | PHE2656 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 905 |
| Chain | Residue |
| B | HOH73 |
| B | GLY2378 |
| B | HIS2379 |
| B | ASP2380 |
| B | ASP2400 |
| B | LYS2404 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 906 |
| Chain | Residue |
| B | HOH74 |
| B | ARG2357 |
| B | ASN2679 |
| B | THR2680 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 907 |
| Chain | Residue |
| B | HOH117 |
| B | ASN2392 |
| B | ARG2393 |
| B | SER2407 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 908 |
| Chain | Residue |
| B | LYS2266 |
| B | PRO2285 |
| B | LYS2286 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 909 |
| Chain | Residue |
| B | HOH15 |
| B | LEU2589 |
| B | LYS2590 |
| B | ASP2591 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 910 |
| Chain | Residue |
| B | HOH186 |
| B | ARG2441 |
| B | GLN2618 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 911 |
| Chain | Residue |
| B | HOH102 |
| B | HOH201 |
| B | ASP2399 |
| B | GLY2423 |
| B | TRP2425 |
| B | THR2439 |
| C | PRO63 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 912 |
| Chain | Residue |
| B | HOH191 |
| B | SER2462 |
| B | THR2463 |
| B | ARG2479 |
| C | ASP64 |
| C | LYS65 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. IISGstDrTLKVWNA |
| Chain | Residue | Details |
| B | ILE2434-ALA2448 | |
| B | VAL2474-ILE2488 | |
| B | VAL2554-VAL2568 | |
| B | LEU2594-ILE2608 | |
| B | VAL2637-LEU2651 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Domain: {"description":"F-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00080","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 1"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 36 |
| Details | Repeat: {"description":"WD 2"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"WD 3"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 36 |
| Details | Repeat: {"description":"WD 4"} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"WD 5"} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 38 |
| Details | Repeat: {"description":"WD 6"} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 37 |
| Details | Repeat: {"description":"WD 7"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g72 |
| Chain | Residue | Details |
| B | SER2407 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g72 |
| Chain | Residue | Details |
| B | ASP2567 | |
