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2OVR

Structure of the Skp1-Fbw7-CyclinEdegN complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0006511biological_processubiquitin-dependent protein catabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 B 901
ChainResidue
BHOH83
BHOH143
BHOH196
BARG2505
BARG2674

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 902
ChainResidue
BHOH46
BGLN2428
BARG2676

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 B 903
ChainResidue
BTHR2416
BARG2415

site_idAC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 B 904
ChainResidue
BHOH5
BHOH12
BHOH25
BHOH87
BGLN2618
BPRO2620
BGLU2655
BPHE2656

site_idAC5
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 B 905
ChainResidue
BHOH73
BGLY2378
BHIS2379
BASP2380
BASP2400
BLYS2404

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 906
ChainResidue
BHOH74
BARG2357
BASN2679
BTHR2680

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 907
ChainResidue
BHOH117
BASN2392
BARG2393
BSER2407

site_idAC8
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 908
ChainResidue
BLYS2266
BPRO2285
BLYS2286

site_idAC9
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 909
ChainResidue
BHOH15
BLEU2589
BLYS2590
BASP2591

site_idBC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 910
ChainResidue
BHOH186
BARG2441
BGLN2618

site_idBC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 B 911
ChainResidue
BHOH102
BHOH201
BASP2399
BGLY2423
BTRP2425
BTHR2439
CPRO63

site_idBC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 B 912
ChainResidue
BHOH191
BSER2462
BTHR2463
BARG2479
CASP64
CLYS65

Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. IISGstDrTLKVWNA
ChainResidueDetails
BILE2434-ALA2448
BVAL2474-ILE2488
BVAL2554-VAL2568
BLEU2594-ILE2608
BVAL2637-LEU2651

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692
ChainResidueDetails
ATHR1131

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744|PubMed:25114211
ChainResidueDetails
ALYS1142

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1g72
ChainResidueDetails
BSER2407

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1g72
ChainResidueDetails
BASP2567

227344

PDB entries from 2024-11-13

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