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2OUI

D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
NADP-dependent alcohol dehydrogenasepolymer36038603.64UniProt (P35630)
Pfam (PF08240)
Pfam (PF00107)
Entamoeba histolytica
2AA, E, N, V
(D, A, B, C)
ZINC IONnon-polymer65.44Chemie (ZN)
3BA, F, G, O
(D, A, B)
NITRATE IONnon-polymer62.04Chemie (NO3)
4CA, H, P, W
(D, A, B, C)
CACODYLATE IONnon-polymer137.04Chemie (CAC)
5EA, I, J, K, L...
(D, A, B, C)
1,2-ETHANEDIOLnon-polymer62.19Chemie (EDO)
6M, T, U, Z
(A, B, C)
TRIETHYLENE GLYCOLnon-polymer150.24Chemie (PGE)
7Y
(C)
PENTAETHYLENE GLYCOLnon-polymer238.31Chemie (1PE)
8DA
(D)
CHLORIDE IONnon-polymer35.51Chemie (CL)
9FA
(D)
TETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
10GA, HA, IA, JA
(A, B, C, D)
waterwater18.01075Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 360 (UniProt: P35630)
PDBExternal DatabaseDetails
Pro 275Asp 275engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight154414.4
Non-Polymers*Number of molecules28
Total formula weight2684.9
All*Total formula weight157099.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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