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2OT3

Crystal structure of rabex-5 VPS9 domain in complex with nucleotide free RAB21

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Rab5 GDP/GTP exchange factorpolymer27432082.81UniProt (Q9UJ41)
Pfam (PF18151)
Pfam (PF02204)
Homo sapiens (human)Rabex-5, Rabaptin-5-associated exchange factor for Rab5, RAP1
2B
(B)
Ras-related protein Rab-21polymer17019335.21UniProt (Q9UL25)
Pfam (PF00071)
Homo sapiens (human)
3C, D
(A, B)
waterwater18.0463Chemie (HOH)
Sequence modifications
A: 132 - 397 (UniProt: Q9UJ41)
PDBExternal DatabaseDetails
Gly 124-cloning artifact
Ser 125-cloning artifact
His 126-expression tag
His 127-expression tag
His 128-expression tag
His 129-expression tag
His 130-expression tag
His 131-expression tag
B: 16 - 183 (UniProt: Q9UL25)
PDBExternal DatabaseDetails
Gly 14-cloning artifact
Ser 15-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51418.0
All*Total formula weight51418.0
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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