2OT3

Crystal structure of rabex-5 VPS9 domain in complex with nucleotide free RAB21

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0016192	biological_process	vesicle-mediated transport
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0032482	biological_process	Rab protein signal transduction

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	143
Details	Domain: {"description":"VPS9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00550","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9JM13","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	18
Details	Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	GLN78

---