2OQ1
Tandem SH2 domains of ZAP-70 with 19-mer zeta1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase ZAP-70 | polymer | 254 | 28906.7 | 1 | UniProt (P43403) Pfam (PF00017) | Homo sapiens (human) | 70 kDa zeta-associated protein, Syk-related tyrosine kinase |
| 2 | B (B) | T-cell surface glycoprotein CD3 zeta chain | polymer | 19 | 2515.5 | 1 | UniProt (P20963) Pfam (PF02189) | T-cell receptor T3 zeta chain, CD247 antigen | |
| 3 | C (A) | LEAD (II) ION | non-polymer | 207.2 | 1 | Chemie (PB) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A: 5 - 258 (UniProt: P43403)
B: 301 - 319 (UniProt: P20963)
| PDB | External Database | Details |
|---|---|---|
| Mse 31 | Met 29 | modified residue |
| Mse 124 | Met 122 | modified residue |
| Mse 163 | Met 161 | modified residue |
| PDB | External Database | Details |
|---|---|---|
| Ptr 304 | Tyr 72 | modified residue |
| Ptr 315 | Tyr 83 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31422.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 207.2 | |
| All* | Total formula weight | 31629.3 |
