2OO4
Structure of LNR-HD (Negative Regulatory Region) from human Notch 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neurogenic locus notch homolog protein 2 | polymer | 234 | 25872.7 | 2 | UniProt (Q04721) Pfam (PF00066) Pfam (PF06816) Pfam (PF07684) | Homo sapiens (human) | Notch 2, hN2, Notch 2 extracellular truncation, Notch 2 intracellular domain |
| 2 | C, D, E, O, P... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 3 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | G, H, I, J, K... (A, B) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 5 | T, U (A, B) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A, B: 1423 - 1677 (UniProt: Q04721)
| PDB | External Database | Details |
|---|---|---|
| Gly 1422 | - | expression tag |
| Asn 1519 | Asp 1519 | conflict |
| - | Glu 1595 | deletion |
| - | Lys 1596 | deletion |
| - | Ser 1597 | deletion |
| - | Ala 1598 | deletion |
| - | Ala 1599 | deletion |
| - | Met 1600 | deletion |
| - | Lys 1601 | deletion |
| - | Lys 1602 | deletion |
| - | Gln 1603 | deletion |
| - | Arg 1604 | deletion |
| - | Met 1605 | deletion |
| - | Thr 1606 | deletion |
| - | Arg 1607 | deletion |
| - | Arg 1608 | deletion |
| - | Ser 1609 | deletion |
| - | Leu 1610 | deletion |
| - | Pro 1611 | deletion |
| - | Gly 1612 | deletion |
| - | Glu 1613 | deletion |
| - | Gln 1614 | deletion |
| - | Glu 1615 | deletion |
| - | Gln 1616 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51745.5 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1226.8 | |
| All* | Total formula weight | 52972.3 |
