2ONM
Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Aldehyde dehydrogenase, mitochondrial precursor | polymer | 500 | 54499.7 | 12 | UniProt (P05091) Pfam (PF00171) In PDB | Homo sapiens (human) | ALDH class 2, ALDHI, ALDH-E2 |
| 2 | D, H, E, I, A... | SODIUM ION | non-polymer | 23.0 | 17 | Chemie (NA) | |||
| 3 | D, E, I, A, J... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 7 | Chemie (ADP) | |||
| 4 | C, D, H, E, I... | 1,2-ETHANEDIOL | non-polymer | 62.1 | 25 | Chemie (EDO) | |||
| 5 | G, D, H, E, I... | GUANIDINE | non-polymer | 59.1 | 9 | Chemie (GAI) | |||
| 6 | H, F, B, G, C | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 5 | Chemie (NAD) | |||
| 7 | water | water | 18.0 | 1932 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 500 (UniProt: P05091)
| PDB | External Database | Details |
|---|---|---|
| Lys 487 | Glu 504 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 653996.3 | |
| Non-Polymers* | Number of molecules | 63 |
| Total formula weight | 8781.7 | |
| All* | Total formula weight | 662778.0 |
