2ONM
Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| A | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006066 | biological_process | alcohol metabolic process |
| A | 0006068 | biological_process | ethanol catabolic process |
| A | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0018547 | molecular_function | nitroglycerin reductase activity |
| A | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| A | 0046185 | biological_process | aldehyde catabolic process |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0106435 | molecular_function | carboxylesterase activity |
| A | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| A | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| B | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| B | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005759 | cellular_component | mitochondrial matrix |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006066 | biological_process | alcohol metabolic process |
| B | 0006068 | biological_process | ethanol catabolic process |
| B | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0018547 | molecular_function | nitroglycerin reductase activity |
| B | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| B | 0046185 | biological_process | aldehyde catabolic process |
| B | 0051287 | molecular_function | NAD binding |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0106435 | molecular_function | carboxylesterase activity |
| B | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| B | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| C | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| C | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005759 | cellular_component | mitochondrial matrix |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006066 | biological_process | alcohol metabolic process |
| C | 0006068 | biological_process | ethanol catabolic process |
| C | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0018547 | molecular_function | nitroglycerin reductase activity |
| C | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| C | 0046185 | biological_process | aldehyde catabolic process |
| C | 0051287 | molecular_function | NAD binding |
| C | 0070062 | cellular_component | extracellular exosome |
| C | 0106435 | molecular_function | carboxylesterase activity |
| C | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| C | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| D | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| D | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005759 | cellular_component | mitochondrial matrix |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006066 | biological_process | alcohol metabolic process |
| D | 0006068 | biological_process | ethanol catabolic process |
| D | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0018547 | molecular_function | nitroglycerin reductase activity |
| D | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| D | 0046185 | biological_process | aldehyde catabolic process |
| D | 0051287 | molecular_function | NAD binding |
| D | 0070062 | cellular_component | extracellular exosome |
| D | 0106435 | molecular_function | carboxylesterase activity |
| D | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| D | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| E | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| E | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0005759 | cellular_component | mitochondrial matrix |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0006066 | biological_process | alcohol metabolic process |
| E | 0006068 | biological_process | ethanol catabolic process |
| E | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| E | 0009055 | molecular_function | electron transfer activity |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| E | 0018547 | molecular_function | nitroglycerin reductase activity |
| E | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| E | 0046185 | biological_process | aldehyde catabolic process |
| E | 0051287 | molecular_function | NAD binding |
| E | 0070062 | cellular_component | extracellular exosome |
| E | 0106435 | molecular_function | carboxylesterase activity |
| E | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| E | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| F | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| F | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| F | 0005739 | cellular_component | mitochondrion |
| F | 0005759 | cellular_component | mitochondrial matrix |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0006066 | biological_process | alcohol metabolic process |
| F | 0006068 | biological_process | ethanol catabolic process |
| F | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| F | 0009055 | molecular_function | electron transfer activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| F | 0018547 | molecular_function | nitroglycerin reductase activity |
| F | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| F | 0046185 | biological_process | aldehyde catabolic process |
| F | 0051287 | molecular_function | NAD binding |
| F | 0070062 | cellular_component | extracellular exosome |
| F | 0106435 | molecular_function | carboxylesterase activity |
| F | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| F | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| G | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| G | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| G | 0005739 | cellular_component | mitochondrion |
| G | 0005759 | cellular_component | mitochondrial matrix |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0006066 | biological_process | alcohol metabolic process |
| G | 0006068 | biological_process | ethanol catabolic process |
| G | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| G | 0009055 | molecular_function | electron transfer activity |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| G | 0018547 | molecular_function | nitroglycerin reductase activity |
| G | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| G | 0046185 | biological_process | aldehyde catabolic process |
| G | 0051287 | molecular_function | NAD binding |
| G | 0070062 | cellular_component | extracellular exosome |
| G | 0106435 | molecular_function | carboxylesterase activity |
| G | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| G | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| H | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| H | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| H | 0005739 | cellular_component | mitochondrion |
| H | 0005759 | cellular_component | mitochondrial matrix |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0006066 | biological_process | alcohol metabolic process |
| H | 0006068 | biological_process | ethanol catabolic process |
| H | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| H | 0009055 | molecular_function | electron transfer activity |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| H | 0018547 | molecular_function | nitroglycerin reductase activity |
| H | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| H | 0046185 | biological_process | aldehyde catabolic process |
| H | 0051287 | molecular_function | NAD binding |
| H | 0070062 | cellular_component | extracellular exosome |
| H | 0106435 | molecular_function | carboxylesterase activity |
| H | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| H | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| I | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| I | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| I | 0005739 | cellular_component | mitochondrion |
| I | 0005759 | cellular_component | mitochondrial matrix |
| I | 0005975 | biological_process | carbohydrate metabolic process |
| I | 0006066 | biological_process | alcohol metabolic process |
| I | 0006068 | biological_process | ethanol catabolic process |
| I | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| I | 0009055 | molecular_function | electron transfer activity |
| I | 0016491 | molecular_function | oxidoreductase activity |
| I | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| I | 0018547 | molecular_function | nitroglycerin reductase activity |
| I | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| I | 0046185 | biological_process | aldehyde catabolic process |
| I | 0051287 | molecular_function | NAD binding |
| I | 0070062 | cellular_component | extracellular exosome |
| I | 0106435 | molecular_function | carboxylesterase activity |
| I | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| I | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| J | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| J | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| J | 0005739 | cellular_component | mitochondrion |
| J | 0005759 | cellular_component | mitochondrial matrix |
| J | 0005975 | biological_process | carbohydrate metabolic process |
| J | 0006066 | biological_process | alcohol metabolic process |
| J | 0006068 | biological_process | ethanol catabolic process |
| J | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| J | 0009055 | molecular_function | electron transfer activity |
| J | 0016491 | molecular_function | oxidoreductase activity |
| J | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| J | 0018547 | molecular_function | nitroglycerin reductase activity |
| J | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| J | 0046185 | biological_process | aldehyde catabolic process |
| J | 0051287 | molecular_function | NAD binding |
| J | 0070062 | cellular_component | extracellular exosome |
| J | 0106435 | molecular_function | carboxylesterase activity |
| J | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| J | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| K | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| K | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| K | 0005739 | cellular_component | mitochondrion |
| K | 0005759 | cellular_component | mitochondrial matrix |
| K | 0005975 | biological_process | carbohydrate metabolic process |
| K | 0006066 | biological_process | alcohol metabolic process |
| K | 0006068 | biological_process | ethanol catabolic process |
| K | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| K | 0009055 | molecular_function | electron transfer activity |
| K | 0016491 | molecular_function | oxidoreductase activity |
| K | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| K | 0018547 | molecular_function | nitroglycerin reductase activity |
| K | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| K | 0046185 | biological_process | aldehyde catabolic process |
| K | 0051287 | molecular_function | NAD binding |
| K | 0070062 | cellular_component | extracellular exosome |
| K | 0106435 | molecular_function | carboxylesterase activity |
| K | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| K | 1905627 | biological_process | regulation of serotonin biosynthetic process |
| L | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| L | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| L | 0005739 | cellular_component | mitochondrion |
| L | 0005759 | cellular_component | mitochondrial matrix |
| L | 0005975 | biological_process | carbohydrate metabolic process |
| L | 0006066 | biological_process | alcohol metabolic process |
| L | 0006068 | biological_process | ethanol catabolic process |
| L | 0008957 | molecular_function | phenylacetaldehyde dehydrogenase (NAD+) activity |
| L | 0009055 | molecular_function | electron transfer activity |
| L | 0016491 | molecular_function | oxidoreductase activity |
| L | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| L | 0018547 | molecular_function | nitroglycerin reductase activity |
| L | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| L | 0046185 | biological_process | aldehyde catabolic process |
| L | 0051287 | molecular_function | NAD binding |
| L | 0070062 | cellular_component | extracellular exosome |
| L | 0106435 | molecular_function | carboxylesterase activity |
| L | 1903179 | biological_process | regulation of dopamine biosynthetic process |
| L | 1905627 | biological_process | regulation of serotonin biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 5003 |
| Chain | Residue |
| B | GLY299 |
| B | PHE401 |
| B | GLY402 |
| B | HOH2286 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA C 5004 |
| Chain | Residue |
| C | ASN275 |
| C | ALA290 |
| C | GLY305 |
| C | THR308 |
| C | MET405 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA F 5007 |
| Chain | Residue |
| F | GLY299 |
| F | PHE401 |
| F | GLY402 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA G 5008 |
| Chain | Residue |
| G | ASN275 |
| G | ALA290 |
| G | ALA293 |
| G | GLY305 |
| G | THR308 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA K 5012 |
| Chain | Residue |
| K | ASN275 |
| K | ALA290 |
| K | ALA293 |
| K | GLY305 |
| K | THR308 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 601 |
| Chain | Residue |
| A | THR39 |
| A | VAL40 |
| A | ASP109 |
| A | GLN196 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 602 |
| Chain | Residue |
| B | THR39 |
| B | VAL40 |
| B | ASP109 |
| B | GLN196 |
| B | HOH2722 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C 603 |
| Chain | Residue |
| C | VAL40 |
| C | ASP109 |
| C | GLN196 |
| C | HOH1247 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA D 604 |
| Chain | Residue |
| D | VAL40 |
| D | ASP109 |
| D | GLN196 |
| D | VAL345 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA E 605 |
| Chain | Residue |
| E | THR39 |
| E | VAL40 |
| E | ASP109 |
| E | GLN196 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA F 606 |
| Chain | Residue |
| F | THR39 |
| F | VAL40 |
| F | ASP109 |
| F | GLN196 |
| F | HOH2029 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA G 607 |
| Chain | Residue |
| G | THR39 |
| G | VAL40 |
| G | ASP109 |
| G | GLN196 |
| G | HOH2330 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA H 608 |
| Chain | Residue |
| H | THR39 |
| H | VAL40 |
| H | ASP109 |
| H | GLN196 |
| H | HOH1859 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA I 609 |
| Chain | Residue |
| I | THR39 |
| I | VAL40 |
| I | ASP109 |
| I | GLN196 |
| I | HOH2491 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA J 610 |
| Chain | Residue |
| J | VAL40 |
| J | PRO42 |
| J | ASP109 |
| J | GLN196 |
| J | VAL345 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA K 611 |
| Chain | Residue |
| K | VAL40 |
| K | ASP109 |
| K | GLN196 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA L 612 |
| Chain | Residue |
| L | THR39 |
| L | VAL40 |
| L | ASP109 |
| L | GLN196 |
| site_id | BC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP A 501 |
| Chain | Residue |
| A | ILE165 |
| A | ILE166 |
| A | TRP168 |
| A | LYS192 |
| A | GLU195 |
| A | GLY225 |
| A | GLY229 |
| A | ALA230 |
| A | PHE243 |
| A | THR244 |
| A | GLY245 |
| A | SER246 |
| A | ILE249 |
| A | ILE253 |
| site_id | CC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAD B 502 |
| Chain | Residue |
| B | ALA230 |
| B | PHE243 |
| B | THR244 |
| B | GLY245 |
| B | SER246 |
| B | ILE249 |
| B | ILE253 |
| B | GLY270 |
| B | CYS302 |
| B | GLN349 |
| B | GLU399 |
| B | PHE401 |
| B | HOH1088 |
| B | ILE165 |
| B | ILE166 |
| B | PRO167 |
| B | TRP168 |
| B | ASN169 |
| B | LYS192 |
| B | GLU195 |
| B | GLN196 |
| B | GLY225 |
| B | GLY229 |
| site_id | CC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD C 503 |
| Chain | Residue |
| C | ILE165 |
| C | ILE166 |
| C | PRO167 |
| C | TRP168 |
| C | ASN169 |
| C | LYS192 |
| C | GLU195 |
| C | GLN196 |
| C | GLY225 |
| C | GLY229 |
| C | ALA230 |
| C | PHE243 |
| C | GLY245 |
| C | SER246 |
| C | ILE249 |
| C | ILE253 |
| C | GLU268 |
| C | CYS302 |
| C | GLN349 |
| C | LYS352 |
| C | GLU399 |
| C | PHE401 |
| C | HOH1943 |
| C | HOH2207 |
| C | HOH2848 |
| site_id | CC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP D 504 |
| Chain | Residue |
| D | ILE165 |
| D | ILE166 |
| D | TRP168 |
| D | LYS192 |
| D | GLU195 |
| D | GLN196 |
| D | GLY225 |
| D | GLY229 |
| D | ALA230 |
| D | PHE243 |
| D | GLY245 |
| D | SER246 |
| D | ILE249 |
| D | ILE253 |
| site_id | CC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP E 505 |
| Chain | Residue |
| E | ILE165 |
| E | ILE166 |
| E | TRP168 |
| E | LYS192 |
| E | GLU195 |
| E | GLN196 |
| E | GLY225 |
| E | GLY229 |
| E | ALA230 |
| E | PHE243 |
| E | GLY245 |
| E | SER246 |
| E | ILE249 |
| E | ILE253 |
| E | HOH1251 |
| E | HOH1286 |
| site_id | CC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAD F 506 |
| Chain | Residue |
| F | ILE165 |
| F | ILE166 |
| F | PRO167 |
| F | TRP168 |
| F | ASN169 |
| F | LYS192 |
| F | ALA194 |
| F | GLU195 |
| F | GLN196 |
| F | GLY225 |
| F | GLY229 |
| F | ALA230 |
| F | PHE243 |
| F | GLY245 |
| F | SER246 |
| F | ILE249 |
| F | ILE253 |
| F | GLU268 |
| F | LEU269 |
| F | GLY270 |
| F | CYS302 |
| F | GLN349 |
| F | LYS352 |
| F | GLU399 |
| F | PHE401 |
| F | HOH1015 |
| F | HOH1051 |
| F | HOH1652 |
| site_id | CC6 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAD G 507 |
| Chain | Residue |
| G | ILE165 |
| G | ILE166 |
| G | PRO167 |
| G | TRP168 |
| G | ASN169 |
| G | LYS192 |
| G | GLU195 |
| G | GLY225 |
| G | GLY229 |
| G | ALA230 |
| G | PHE243 |
| G | GLY245 |
| G | SER246 |
| G | ILE249 |
| G | ILE253 |
| G | LEU269 |
| G | GLY270 |
| G | CYS302 |
| G | GLN349 |
| G | LYS352 |
| G | GLU399 |
| G | PHE401 |
| site_id | CC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAD H 508 |
| Chain | Residue |
| H | ILE165 |
| H | ILE166 |
| H | PRO167 |
| H | TRP168 |
| H | ASN169 |
| H | LYS192 |
| H | GLU195 |
| H | GLY225 |
| H | GLY229 |
| H | ALA230 |
| H | PHE243 |
| H | GLY245 |
| H | SER246 |
| H | ILE249 |
| H | ILE253 |
| H | GLY270 |
| H | CYS302 |
| H | GLN349 |
| H | LYS352 |
| H | GLU399 |
| H | PHE401 |
| H | HOH1055 |
| site_id | CC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP I 509 |
| Chain | Residue |
| I | ILE165 |
| I | ILE166 |
| I | TRP168 |
| I | LYS192 |
| I | ALA194 |
| I | GLU195 |
| I | GLY225 |
| I | PRO226 |
| I | GLY229 |
| I | ALA230 |
| I | PHE243 |
| I | THR244 |
| I | GLY245 |
| I | SER246 |
| I | ILE249 |
| I | ILE253 |
| site_id | CC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP J 510 |
| Chain | Residue |
| J | ILE165 |
| J | ILE166 |
| J | TRP168 |
| J | LYS192 |
| J | GLU195 |
| J | GLN196 |
| J | GLY225 |
| J | GLY229 |
| J | ALA230 |
| J | PHE243 |
| J | GLY245 |
| J | SER246 |
| J | ILE249 |
| J | ILE253 |
| site_id | DC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP K 511 |
| Chain | Residue |
| K | ILE165 |
| K | ILE166 |
| K | TRP168 |
| K | LYS192 |
| K | GLU195 |
| K | GLY225 |
| K | GLY229 |
| K | ALA230 |
| K | PHE243 |
| K | GLY245 |
| K | SER246 |
| K | ILE249 |
| K | ILE253 |
| K | HOH1244 |
| site_id | DC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADP L 512 |
| Chain | Residue |
| L | ILE165 |
| L | ILE166 |
| L | TRP168 |
| L | LYS192 |
| L | GLU195 |
| L | GLY225 |
| L | GLY229 |
| L | ALA230 |
| L | PHE243 |
| L | SER246 |
| L | ILE249 |
| L | ILE253 |
| L | HOH2926 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 701 |
| Chain | Residue |
| A | TYR153 |
| A | ARG155 |
| B | ASN440 |
| B | SER443 |
| D | PHE151 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 901 |
| Chain | Residue |
| A | PHE18 |
| A | TYR101 |
| A | TYR203 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 802 |
| Chain | Residue |
| B | GLN14 |
| B | ASN41 |
| B | VAL47 |
| B | ILE48 |
| B | LEU108 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 803 |
| Chain | Residue |
| C | ASN41 |
| C | THR44 |
| C | GLU46 |
| C | LEU108 |
| C | HOH2212 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 902 |
| Chain | Residue |
| B | ASP98 |
| B | TYR101 |
| B | TYR203 |
| H | HOH1184 |
| H | HOH2159 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 903 |
| Chain | Residue |
| C | ASP98 |
| C | TYR101 |
| site_id | DC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 704 |
| Chain | Residue |
| A | PHE151 |
| C | SER443 |
| D | TYR153 |
| D | ARG155 |
| site_id | EC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 904 |
| Chain | Residue |
| D | PHE18 |
| D | TYR101 |
| D | TYR203 |
| D | HOH2884 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 705 |
| Chain | Residue |
| E | TYR153 |
| E | ARG155 |
| F | ASN440 |
| F | SER443 |
| H | PHE151 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 805 |
| Chain | Residue |
| E | ASN41 |
| E | THR44 |
| E | GLU46 |
| E | ILE48 |
| site_id | EC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 905 |
| Chain | Residue |
| E | PHE18 |
| E | TYR101 |
| E | TYR203 |
| E | HOH2787 |
| I | GLN14 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO F 706 |
| Chain | Residue |
| E | SER443 |
| F | TYR153 |
| F | ARG155 |
| G | PHE151 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO F 806 |
| Chain | Residue |
| F | GLN14 |
| F | ASN41 |
| F | THR44 |
| F | GLU46 |
| F | LEU108 |
| F | HOH2389 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO F 906 |
| Chain | Residue |
| F | PHE18 |
| F | TYR101 |
| F | TYR203 |
| F | HOH2346 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO F 707 |
| Chain | Residue |
| F | PHE151 |
| G | TYR153 |
| G | ARG155 |
| H | ASN440 |
| H | SER443 |
| site_id | EC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO G 807 |
| Chain | Residue |
| G | ASN41 |
| G | THR44 |
| G | ILE48 |
| G | LEU108 |
| G | HOH2633 |
| site_id | FC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO G 907 |
| Chain | Residue |
| G | TYR101 |
| G | HOH2909 |
| site_id | FC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO H 708 |
| Chain | Residue |
| E | PHE151 |
| G | ASN440 |
| G | SER443 |
| H | TYR153 |
| H | ARG155 |
| site_id | FC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO H 808 |
| Chain | Residue |
| H | ASN41 |
| H | THR44 |
| H | GLU46 |
| H | HOH2123 |
| site_id | FC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO H 908 |
| Chain | Residue |
| D | LEU367 |
| H | PHE18 |
| H | ASP98 |
| H | TYR101 |
| H | TYR203 |
| H | HOH1772 |
| H | HOH2005 |
| site_id | FC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO I 809 |
| Chain | Residue |
| I | THR44 |
| I | GLU46 |
| site_id | FC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO I 909 |
| Chain | Residue |
| I | PHE18 |
| I | TYR101 |
| I | TYR203 |
| I | HOH1775 |
| I | HOH2128 |
| site_id | FC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO K 911 |
| Chain | Residue |
| K | TYR101 |
| K | TYR203 |
| K | HOH2794 |
| site_id | FC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO L 712 |
| Chain | Residue |
| K | ASN440 |
| K | SER443 |
| L | TYR153 |
| L | ARG155 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO L 912 |
| Chain | Residue |
| L | PHE18 |
| L | TYR101 |
| L | TYR203 |
| site_id | GC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GAI A 902 |
| Chain | Residue |
| A | ILE146 |
| A | ASP147 |
| B | VAL458 |
| B | PHE459 |
| site_id | GC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GAI E 906 |
| Chain | Residue |
| E | ASP147 |
| E | PHE150 |
| F | PHE459 |
| F | HOH2713 |
| site_id | GC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GAI G 5009 |
| Chain | Residue |
| G | ILE146 |
| G | ASP147 |
| G | PHE150 |
| G | HOH2440 |
| G | HOH2819 |
| H | PHE459 |
| site_id | GC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI H 909 |
| Chain | Residue |
| G | PHE459 |
| H | ILE146 |
| H | ASP147 |
| H | PHE150 |
| H | HOH2313 |
| site_id | GC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GAI I 910 |
| Chain | Residue |
| I | ASP147 |
| I | GLY148 |
| I | PHE150 |
| site_id | GC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GAI J 611 |
| Chain | Residue |
| I | PHE459 |
| J | ILE146 |
| J | ASP147 |
| site_id | GC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI D 905 |
| Chain | Residue |
| A | ASN440 |
| B | VAL493 |
| C | PHE151 |
| D | ASN440 |
| D | HOH2800 |
| site_id | GC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GAI E 907 |
| Chain | Residue |
| E | ASN440 |
| E | HOH2847 |
| H | ASN440 |
| site_id | GC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GAI G 5010 |
| Chain | Residue |
| F | ASN440 |
| F | HOH1342 |
| G | ASN440 |
| G | HOH1845 |
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. FfNQGQCCCAGS |
| Chain | Residue | Details |
| A | PHE295-SER306 |
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELGGKSP |
| Chain | Residue | Details |
| A | LEU267-PRO274 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | GLU268 | |
| J | GLU268 | |
| K | GLU268 | |
| L | GLU268 | |
| B | GLU268 | |
| C | GLU268 | |
| D | GLU268 | |
| E | GLU268 | |
| F | GLU268 | |
| G | GLU268 | |
| H | GLU268 | |
| I | GLU268 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | ACT_SITE: Nucleophile |
| Chain | Residue | Details |
| A | CYS302 | |
| J | CYS302 | |
| K | CYS302 | |
| L | CYS302 | |
| B | CYS302 | |
| C | CYS302 | |
| D | CYS302 | |
| E | CYS302 | |
| F | CYS302 | |
| G | CYS302 | |
| H | CYS302 | |
| I | CYS302 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY245 | |
| J | GLY245 | |
| K | GLY245 | |
| L | GLY245 | |
| B | GLY245 | |
| C | GLY245 | |
| D | GLY245 | |
| E | GLY245 | |
| F | GLY245 | |
| G | GLY245 | |
| H | GLY245 | |
| I | GLY245 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | SITE: Transition state stabilizer => ECO:0000250|UniProtKB:P20000 |
| Chain | Residue | Details |
| A | ASN169 | |
| J | ASN169 | |
| K | ASN169 | |
| L | ASN169 | |
| B | ASN169 | |
| C | ASN169 | |
| D | ASN169 | |
| E | ASN169 | |
| F | ASN169 | |
| G | ASN169 | |
| H | ASN169 | |
| I | ASN169 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 108 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P47738 |
| Chain | Residue | Details |
| A | LYS35 | |
| B | LYS35 | |
| L | LYS35 | |
| L | LYS56 | |
| L | LYS61 | |
| L | LYS142 | |
| L | LYS351 | |
| L | LYS366 | |
| L | LYS409 | |
| L | LYS411 | |
| L | LYS434 | |
| B | LYS56 | |
| B | LYS61 | |
| B | LYS142 | |
| B | LYS351 | |
| B | LYS366 | |
| B | LYS409 | |
| B | LYS411 | |
| B | LYS434 | |
| C | LYS35 | |
| A | LYS56 | |
| C | LYS56 | |
| C | LYS61 | |
| C | LYS142 | |
| C | LYS351 | |
| C | LYS366 | |
| C | LYS409 | |
| C | LYS411 | |
| C | LYS434 | |
| D | LYS35 | |
| D | LYS56 | |
| A | LYS61 | |
| D | LYS61 | |
| D | LYS142 | |
| D | LYS351 | |
| D | LYS366 | |
| D | LYS409 | |
| D | LYS411 | |
| D | LYS434 | |
| E | LYS35 | |
| E | LYS56 | |
| E | LYS61 | |
| A | LYS142 | |
| E | LYS142 | |
| E | LYS351 | |
| E | LYS366 | |
| E | LYS409 | |
| E | LYS411 | |
| E | LYS434 | |
| F | LYS35 | |
| F | LYS56 | |
| F | LYS61 | |
| F | LYS142 | |
| A | LYS351 | |
| F | LYS351 | |
| F | LYS366 | |
| F | LYS409 | |
| F | LYS411 | |
| F | LYS434 | |
| G | LYS35 | |
| G | LYS56 | |
| G | LYS61 | |
| G | LYS142 | |
| G | LYS351 | |
| A | LYS366 | |
| G | LYS366 | |
| G | LYS409 | |
| G | LYS411 | |
| G | LYS434 | |
| H | LYS35 | |
| H | LYS56 | |
| H | LYS61 | |
| H | LYS142 | |
| H | LYS351 | |
| H | LYS366 | |
| A | LYS409 | |
| H | LYS409 | |
| H | LYS411 | |
| H | LYS434 | |
| I | LYS35 | |
| I | LYS56 | |
| I | LYS61 | |
| I | LYS142 | |
| I | LYS351 | |
| I | LYS366 | |
| I | LYS409 | |
| A | LYS411 | |
| I | LYS411 | |
| I | LYS434 | |
| J | LYS35 | |
| J | LYS56 | |
| J | LYS61 | |
| J | LYS142 | |
| J | LYS351 | |
| J | LYS366 | |
| J | LYS409 | |
| J | LYS411 | |
| A | LYS434 | |
| J | LYS434 | |
| K | LYS35 | |
| K | LYS56 | |
| K | LYS61 | |
| K | LYS142 | |
| K | LYS351 | |
| K | LYS366 | |
| K | LYS409 | |
| K | LYS411 | |
| K | LYS434 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| A | CYS302 | |
| A | GLU268 | |
| A | ASN169 |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| J | CYS302 | |
| J | GLU268 | |
| J | ASN169 |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| K | CYS302 | |
| K | GLU268 | |
| K | ASN169 |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| L | CYS302 | |
| L | GLU268 | |
| L | ASN169 |
| site_id | CSA13 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| A | CYS302 | |
| A | LYS192 | |
| A | GLU268 | |
| A | GLU399 |
| site_id | CSA14 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| B | CYS302 | |
| B | LYS192 | |
| B | GLU268 | |
| B | GLU399 |
| site_id | CSA15 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| C | CYS302 | |
| C | LYS192 | |
| C | GLU268 | |
| C | GLU399 |
| site_id | CSA16 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| D | CYS302 | |
| D | LYS192 | |
| D | GLU268 | |
| D | GLU399 |
| site_id | CSA17 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| E | CYS302 | |
| E | LYS192 | |
| E | GLU268 | |
| E | GLU399 |
| site_id | CSA18 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| F | CYS302 | |
| F | LYS192 | |
| F | GLU268 | |
| F | GLU399 |
| site_id | CSA19 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| G | CYS302 | |
| G | LYS192 | |
| G | GLU268 | |
| G | GLU399 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| B | CYS302 | |
| B | GLU268 | |
| B | ASN169 |
| site_id | CSA20 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| H | CYS302 | |
| H | LYS192 | |
| H | GLU268 | |
| H | GLU399 |
| site_id | CSA21 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| I | CYS302 | |
| I | LYS192 | |
| I | GLU268 | |
| I | GLU399 |
| site_id | CSA22 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| J | CYS302 | |
| J | LYS192 | |
| J | GLU268 | |
| J | GLU399 |
| site_id | CSA23 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| K | CYS302 | |
| K | LYS192 | |
| K | GLU268 | |
| K | GLU399 |
| site_id | CSA24 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| L | CYS302 | |
| L | LYS192 | |
| L | GLU268 | |
| L | GLU399 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| C | CYS302 | |
| C | GLU268 | |
| C | ASN169 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| D | CYS302 | |
| D | GLU268 | |
| D | ASN169 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| E | CYS302 | |
| E | GLU268 | |
| E | ASN169 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| F | CYS302 | |
| F | GLU268 | |
| F | ASN169 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| G | CYS302 | |
| G | GLU268 | |
| G | ASN169 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| H | CYS302 | |
| H | GLU268 | |
| H | ASN169 |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| I | CYS302 | |
| I | GLU268 | |
| I | ASN169 |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| A | LYS192 | electrostatic stabiliser |
| A | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| A | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | GLU399 | electrostatic stabiliser |
| site_id | MCSA10 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| J | LYS192 | electrostatic stabiliser |
| J | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| J | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| J | GLU399 | electrostatic stabiliser |
| site_id | MCSA11 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| K | LYS192 | electrostatic stabiliser |
| K | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| K | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| K | GLU399 | electrostatic stabiliser |
| site_id | MCSA12 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| L | LYS192 | electrostatic stabiliser |
| L | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| L | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| L | GLU399 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| B | LYS192 | electrostatic stabiliser |
| B | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| B | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | GLU399 | electrostatic stabiliser |
| site_id | MCSA3 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| C | LYS192 | electrostatic stabiliser |
| C | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| C | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| C | GLU399 | electrostatic stabiliser |
| site_id | MCSA4 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| D | LYS192 | electrostatic stabiliser |
| D | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| D | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| D | GLU399 | electrostatic stabiliser |
| site_id | MCSA5 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| E | LYS192 | electrostatic stabiliser |
| E | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| E | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| E | GLU399 | electrostatic stabiliser |
| site_id | MCSA6 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| F | LYS192 | electrostatic stabiliser |
| F | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| F | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| F | GLU399 | electrostatic stabiliser |
| site_id | MCSA7 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| G | LYS192 | electrostatic stabiliser |
| G | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| G | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| G | GLU399 | electrostatic stabiliser |
| site_id | MCSA8 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| H | LYS192 | electrostatic stabiliser |
| H | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| H | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| H | GLU399 | electrostatic stabiliser |
| site_id | MCSA9 |
| Number of Residues | 4 |
| Details | M-CSA 803 |
| Chain | Residue | Details |
| I | LYS192 | electrostatic stabiliser |
| I | GLU268 | electrostatic stabiliser, proton acceptor, proton donor |
| I | CYS302 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| I | GLU399 | electrostatic stabiliser |
