2ONB
Human Thymidylate Synthase at low salt conditions with PDPA bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthetase | polymer | 313 | 36067.4 | 1 | UniProt (Q53Y97) Pfam (PF00303) UniProt (by SIFTS) (P04818) | Homo sapiens (human) | |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | PROPANE-1,3-DIYLBIS(PHOSPHONIC ACID) | non-polymer | 204.1 | 1 | Chemie (7PA) | |||
| 5 | E (A) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 1 - 313 (UniProt: Q53Y97)
| PDB | External Database | Details |
|---|---|---|
| Cme 43 | Cys 43 | modified residue |
| Cme 180 | Cys 180 | modified residue |
| Cme 195 | Cys 195 | modified residue |
| Cme 199 | Cys 199 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36067.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 362.2 | |
| All* | Total formula weight | 36429.6 |
