2OKR
Crystal Structure of the P38a-MAPKAP kinase 2 Heterodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Mitogen-activated protein kinase 14 | polymer | 366 | 41998.9 | 2 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (human) | Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A |
| 2 | B, D (C, F) | MAP kinase-activated protein kinase 2 | polymer | 24 | 2812.5 | 2 | UniProt (P49137) | MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2 | |
| 3 | E, F, G (A, D, F) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A, D: 2 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | cloning artifact |
| Ser -4 | - | cloning artifact |
| His -3 | - | cloning artifact |
| Met -2 | - | cloning artifact |
| Leu -1 | - | cloning artifact |
| Glu 0 | - | cloning artifact |
| Met 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89622.9 | |
| All* | Total formula weight | 89622.9 |
