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2OKR

Crystal Structure of the P38a-MAPKAP kinase 2 Heterodimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, DMitogen-activated protein kinase 14polymer36641998.92UniProt (Q16539)
Pfam (PF00069)
In PDB
Homo sapiens (human)Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2C, FMAP kinase-activated protein kinase 2polymer242812.52UniProt (P49137)
In PDB
MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2
3waterwater18.0197Chemie (HOH)
Sequence modifications
A, D: 2 - 360 (UniProt: Q16539)
PDBExternal DatabaseDetails
Gly -5-cloning artifact
Ser -4-cloning artifact
His -3-cloning artifact
Met -2-cloning artifact
Leu -1-cloning artifact
Glu 0-cloning artifact
Met 1-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight89622.9
All*Total formula weight89622.9
*Water molecules are not included.

221716

PDB entries from 2024-06-26

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