2OKJ
The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate decarboxylase 1 | polymer | 504 | 57383.6 | 2 | UniProt (Q99259) Pfam (PF00282) | Homo sapiens (human) | Glutamate decarboxylase 67 kDa isoform, GAD-67, 67 kDa glutamic acid decarboxylase |
| 2 | C, D (A, B) | GAMMA-AMINO-BUTANOIC ACID | non-polymer | 103.1 | 2 | Chemie (ABU) | |||
| 3 | E (B) | 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID | non-polymer | 334.3 | 1 | Chemie (PLZ) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A, B: 93 - 594 (UniProt: Q99259)
| PDB | External Database | Details |
|---|---|---|
| Llp 405 | Lys 405 | modified residue |
| His 595 | - | expression tag |
| His 596 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114767.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 540.5 | |
| All* | Total formula weight | 115307.8 |
