2OJT
Structure and mechanism of kainate receptor modulation by anions
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glutamate receptor, ionotropic kainate 1 | polymer | 258 | 29211.5 | 2 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (Norway rat) | Glutamate receptor 5, GluR-5, GluR5 |
| 2 | A, B | BROMIDE ION | non-polymer | 79.9 | 2 | Chemie (BR) | |||
| 3 | A, B | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 4 | A, B | (S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE | non-polymer | 353.4 | 2 | Chemie (UBA) | |||
| 5 | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 116 (UniProt: P22756)
A, B: 119 - 258 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Gly 34 | Ala 477 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | SEE REMARK 999 |
| Thr 118 | - | SEE REMARK 999 |
| Ser 258 | Glu 821 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58423.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1343.1 | |
| All* | Total formula weight | 59766.1 |
