2OIN
crystal structure of HCV NS3-4A R155K mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Polyprotein | polymer | 200 | 21205.2 | 2 | UniProt (Q9ELS8) Pfam (PF02907) UniProt (by SIFTS) (P27958) In PDB | Hepatitis C virus | |
2 | C, D | NS4A peptide | polymer | 21 | 2077.6 | 2 | Pfam (PF01006) UniProt (by SIFTS) (P27958) In PDB | synthetic construct | |
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A, B: 27 - 207 (UniProt: Q9ELS8)
PDB | External Database | Details |
---|---|---|
Met 16 | - | cloning artifact |
Ala 17 | - | cloning artifact |
Ser 18 | - | cloning artifact |
Met 19 | - | cloning artifact |
Thr 20 | - | cloning artifact |
Gly 21 | - | cloning artifact |
Gly 22 | - | cloning artifact |
Gln 23 | - | cloning artifact |
Gln 24 | - | cloning artifact |
Met 25 | - | cloning artifact |
Gly 26 | - | cloning artifact |
Arg 145 | Gln 1145 | conflict |
Lys 181 | Arg 1181 | engineered mutation |
Gly 208 | - | cloning artifact |
Ser 209 | - | cloning artifact |
His 210 | - | expression tag |
His 211 | - | expression tag |
His 212 | - | expression tag |
His 213 | - | expression tag |
His 214 | - | expression tag |
His 215 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 46565.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 46696.4 |