2OID
Crystal structure of IRAK4 kinase domain complexed with AMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Interleukin-1 receptor-associated kinase 4 | polymer | 301 | 33956.2 | 4 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4, NY- REN-64 antigen |
| 2 | E, F, G, H (A, B, C, D) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 4 | Chemie (ANP) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 160 - 460 (UniProt: Q9NWZ3)
| PDB | External Database | Details |
|---|---|---|
| Tpo 342 | Thr 342 | modified residue |
| Tpo 345 | Thr 345 | modified residue |
| Sep 346 | Ser 346 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 135824.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2024.8 | |
| All* | Total formula weight | 137849.6 |
