2OF5

Oligomeric Death Domain complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Death domain-containing protein CRADD	polymer	114	13095.8	7	UniProt (P78560) Pfam (PF00531) In PDB	Homo sapiens (human)	Caspase and RIP adapter with death domain, RIP-associated protein with a death domain
2	H, I, J, K, L	Leucine-rich repeat and death domain-containing protein	polymer	118	13400.9	5	UniProt (Q9HB75) Pfam (PF00531) In PDB	Homo sapiens (human)	p53-induced protein with a death domain
3		water	water		18.0	21	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G: 94 - 199 (UniProt: P78560)

PDB	External Database	Details
Leu 200	-	cloning artifact
Glu 201	-	cloning artifact
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag

H, I, J, K, L: 778 - 883 (UniProt: Q9HB75)

PDB	External Database	Details
Met 777	-	cloning artifact
Ala 884	-	cloning artifact
Ala 885	-	cloning artifact
Ala 886	-	cloning artifact
Leu 887	-	cloning artifact
Glu 888	-	cloning artifact
His 889	-	expression tag
His 890	-	expression tag
His 891	-	expression tag
His 892	-	expression tag
His 893	-	expression tag
His 894	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	158675.4
All*	Total formula weight	158675.4

*Water molecules are not included.