2OBV
Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | S-adenosylmethionine synthetase isoform type-1 | polymer | 384 | 42640.7 | 1 | UniProt (Q00266) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | Homo sapiens (human) | Methionine adenosyltransferase 1, AdoMet synthetase 1, Methionine adenosyltransferase I/III, MAT-I/III |
| 2 | B, C (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | D (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | E, F, G (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 5 | H (A) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
A: 16 - 395 (UniProt: Q00266)
| PDB | External Database | Details |
|---|---|---|
| Phe -3 | - | cloning artifact |
| Gln -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| Met 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42640.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1027.1 | |
| All* | Total formula weight | 43667.8 |
