2OBV
Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | S-adenosylmethionine synthetase isoform type-1 | polymer | 384 | 42640.7 | 1 | UniProt (Q00266) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | Homo sapiens (human) | Methionine adenosyltransferase 1, AdoMet synthetase 1, Methionine adenosyltransferase I/III, MAT-I/III |
| 2 | B, C (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 3 | D (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (58766358) PubChem (73897310) PubChem (9865603) PubChem (87224684) PubChem (12312798) PubChem (131697735) PubChem (145712080) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 4 | E, F, G (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) PubChem (8200) | |||
| 5 | H (A) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
A: 16 - 395 (UniProt: Q00266)
| PDB | External Database | Details |
|---|---|---|
| Phe -3 | - | cloning artifact |
| Gln -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| Met 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42640.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1027.1 | |
| All* | Total formula weight | 43667.8 |
