2O93

Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	kappaB enhancer element, DNA 25-mer	polymer	25	7681.9	1
2	B (B)	kappaB enhancer element, DNA 25-mer	polymer	25	7678.0	1
3	C, D, E (L, M, O)	actor of activated T-cells, cytoplasmic 2	polymer	301	34226.9	3	UniProt (Q13469) Pfam (PF00554) Pfam (PF16179)	Homo sapiens (human)	T cell transcription factor NFAT1; NFAT pre-existing subunit; NF-ATp

Sequence modifications

L, M, O: 392 - 678 (UniProt: Q13469)

PDB	External Database	Details
Met 378	-	initiating methionine
Arg 379	-	expression tag
Gly 380	-	expression tag
Ser 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag
Thr 388	-	expression tag
Ala 389	-	expression tag
Pro 390	-	expression tag
His 391	-	expression tag
Ser 394	Leu 394	cloning artifact
Val 395	Pro 395	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	118040.6
All*	Total formula weight	118040.6

*Water molecules are not included.