2O7O
Crystal structure analysis of TetR(D) complex with doxycycline
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tetracycline repressor protein class D | polymer | 207 | 23288.3 | 1 | UniProt (P0ACT4) Pfam (PF00440) Pfam (PF02909) In PDB | Escherichia coli | |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | A | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE | non-polymer | 444.4 | 1 | Chemie (DXT) | |||
| 6 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A: 2 - 208 (UniProt: P0ACT4)
| PDB | External Database | Details |
|---|---|---|
| Ser 2 | Ala 1 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23288.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 635.7 | |
| All* | Total formula weight | 23924.0 |
