2O6L

Crystal Structure of the UDP-Glucuronic Acid Binding Domain of the Human Drug Metabolizing UDP-Glucuronosyltransferase 2B7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	UDP-glucuronosyltransferase 2B7	polymer	170	19125.7	2	UniProt (P16662) Pfam (PF00201)	Homo sapiens (human)	UDPGT, 3,4- catechol estrogen specific, UDPGTh-2
2	C, D (A, B)	water	water		18.0	283	Chemie (HOH)

Sequence modifications

A, B: 285 - 451 (UniProt: P16662)

PDB	External Database	Details
Ser 282	-	cloning artifact
Asn 283	-	cloning artifact
Ala 284	-	cloning artifact
Mse 292	Met 292	modified residue
Mse 312	Met 312	modified residue
Mse 316	Met 316	modified residue
Mse 390	Met 390	modified residue
Mse 406	Met 406	modified residue
Mse 420	Met 420	modified residue
Mse 443	Met 443	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38251.4
All*	Total formula weight	38251.4

*Water molecules are not included.