2O5D
Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HCV | polymer | 576 | 64013.3 | 2 | UniProt (P26663) Pfam (PF00998) | Hepatitis C virus | |
| 2 | C, D (A, B) | (2S)-2-({(5Z)-5-[(5-ETHYL-2-FURYL)METHYLENE]-4-OXO-4,5-DIHYDRO-1,3-THIAZOL-2-YL}AMINO)-2-(4-FLUOROPHENYL)-N-[(4-NITROPHENYL)SULFONYL]ACETAMIDE | non-polymer | 558.6 | 2 | Chemie (VR1) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128026.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1117.1 | |
| All* | Total formula weight | 129143.8 |
