2O52

Crystal structure of human RAB4B in complex with GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ras-related protein Rab-4B	polymer	200	22336.2	2	UniProt (P61018) Pfam (PF00071)	Homo sapiens (human)
2	C, G (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
3	D, H (A, B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
4	E, I (A, B)	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
5	F (A)	UNKNOWN ATOM OR ION	non-polymer			1	Chemie (UNX)
6	J, K (A, B)	water	water		18.0	75	Chemie (HOH)

Sequence modifications

A, B: 6 - 183 (UniProt: P61018)

PDB	External Database	Details
Met -16	-	cloning artifact
Gly -15	-	cloning artifact
Ser -14	-	cloning artifact
Ser -13	-	cloning artifact
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Ser -6	-	cloning artifact
Ser -5	-	cloning artifact
Gly -4	-	cloning artifact
Leu -3	-	cloning artifact
Val -2	-	cloning artifact
Pro -1	-	cloning artifact
Arg 0	-	cloning artifact
Gly 1	-	cloning artifact
Ser 2	-	cloning artifact
Ile 3	-	SEE REMARK 999
Trp 4	-	SEE REMARK 999
Ser 5	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44672.4
Non-Polymers*	Number of molecules	7
	Total formula weight	1091.3
All*	Total formula weight	45763.7

*Water molecules are not included.