2O3K
Yeast Cytosine Deaminase D92E Triple Mutant bound to transition state analogue HPY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cytosine deaminase | polymer | 161 | 17831.4 | 2 | UniProt (Q12178) Pfam (PF00383) In PDB | Saccharomyces cerevisiae (baker's yeast) | Cytosine aminohydrolase |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | 4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE | non-polymer | 114.1 | 2 | Chemie (HPY) | |||
| 4 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 158 (UniProt: Q12178)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Leu 23 | Ala 23 | engineered mutation |
| Glu 92 | Asp 92 | engineered mutation |
| Ile 108 | Val 108 | engineered mutation |
| Leu 140 | Ile 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35662.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 399.1 | |
| All* | Total formula weight | 36061.8 |
