2O2F
Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Apoptosis regulator Bcl-2 | polymer | 138 | 16366.4 | 1 | UniProt (P10415) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | |
2 | A | 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE | non-polymer | 688.9 | 1 | Chemie (LI0) |
Sequence modifications
A: 6 - 29 (UniProt: P10415)
A: 89 - 201 (UniProt: P10415)
A: 89 - 201 (UniProt: P10415)
PDB | External Database | Details |
---|---|---|
Glu 48 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16366.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 688.9 | |
All* | Total formula weight | 17055.3 |