2O22
Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Apoptosis regulator Bcl-2 | polymer | 164 | 19155.3 | 1 | UniProt (P10415) UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | |
| 2 | A | N-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide | non-polymer | 596.8 | 1 | Chemie (LIU) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19155.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 596.8 | |
| All* | Total formula weight | 19752.0 |
