2NXI
Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 2-dehydro-3-deoxyphosphooctonate aldolase | polymer | 263 | 29362.8 | 12 | UniProt (O66496) Pfam (PF00793) | Aquifex aeolicus | Phospho-2- dehydro-3-deoxyoctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8- phosphate synthetase, KDO-8-phosphate synthetase, KDO 8-P synthase, KDOPS |
| 2 | EA, GA, IA, M, S... (J, K, L, A, D...) | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
| 3 | AA, BA, CA, DA, FA... (H, I, J, K, L...) | PHOSPHOENOLPYRUVATE | non-polymer | 168.0 | 17 | Chemie (PEP) | |||
| 4 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 1178 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 264 (UniProt: O66496)
| PDB | External Database | Details |
|---|---|---|
| Met 10 | Pro 10 | engineered mutation |
| Asn 11 | Cys 11 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 352354.0 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 3521.5 | |
| All* | Total formula weight | 355875.5 |
