2NWS
Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 2-dehydro-3-deoxyphosphooctonate aldolase | polymer | 267 | 29785.4 | 2 | UniProt (O66496) Pfam (PF00793) In PDB | Aquifex aeolicus | Phospho-2-dehydro-3-deoxyoctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase, KDO-8-phosphate synthetase, KDO 8-P synthase, KDOPS |
| 2 | A, B | PHOSPHOENOLPYRUVATE | non-polymer | 168.0 | 2 | Chemie (PEP) | |||
| 3 | A, B | ARABINOSE-5-PHOSPHATE | non-polymer | 232.1 | 2 | Chemie (A5P) | |||
| 4 | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A, B: 1001 - 1267 (UniProt: O66496)
| PDB | External Database | Details |
|---|---|---|
| Asn 1011 | Cys 11 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59570.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 800.3 | |
| All* | Total formula weight | 60371.1 |
