2NW9

Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferrous heme and 6-fluoro-tryptophan. Northeast Structural Genomics Target XcR13

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tryptophan 2,3-dioxygenase	polymer	306	35731.4	2	UniProt (Q8PDA8) Pfam (PF03301) In PDB	Xanthomonas campestris pv. campestris
2	A	6-FLUORO-L-TRYPTOPHAN	non-polymer		222.2	1	Chemie (FT6)
3	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
4	B	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
5		water	water		18.0	596	Chemie (HOH)

Sequence modifications

A, B: 1 - 298 (UniProt: Q8PDA8)

PDB	External Database	Details
Leu 299	-	expression tag
Glu 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71462.8
Non-Polymers*	Number of molecules	5
	Total formula weight	1565.1
All*	Total formula weight	73027.9

*Water molecules are not included.