2NW9
Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferrous heme and 6-fluoro-tryptophan. Northeast Structural Genomics Target XcR13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tryptophan 2,3-dioxygenase | polymer | 306 | 35731.4 | 2 | UniProt (Q8PDA8) Pfam (PF03301) | Xanthomonas campestris pv. campestris | |
| 2 | C (A) | 6-FLUORO-L-TRYPTOPHAN | non-polymer | 222.2 | 1 | Chemie (FT6) | |||
| 3 | D, G (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | E, F (B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 596 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 298 (UniProt: Q8PDA8)
| PDB | External Database | Details |
|---|---|---|
| Leu 299 | - | expression tag |
| Glu 300 | - | expression tag |
| His 301 | - | expression tag |
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71462.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1565.1 | |
| All* | Total formula weight | 73027.9 |
