2NW8

Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferrous heme and tryptophan. Northeast Structural Genomics Target XcR13.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tryptophan 2,3-dioxygenase	polymer	306	35731.4	2	UniProt (Q8PDA8) Pfam (PF03301) In PDB	Xanthomonas campestris pv. campestris
2	A, B	TRYPTOPHAN	non-polymer		204.2	4	Chemie (TRP)
3	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
4	B	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
5		water	water		18.0	708	Chemie (HOH)

Sequence modifications

A, B: 1 - 298 (UniProt: Q8PDA8)

PDB	External Database	Details
Leu 299	-	expression tag
Glu 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71462.8
Non-Polymers*	Number of molecules	8
	Total formula weight	2159.8
All*	Total formula weight	73622.6

*Water molecules are not included.