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2NVD

Human Aldose Reductase complexed with novel naphtho[1,2-d]isothiazole acetic acid derivative (2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAldose reductasepolymer31635898.31UniProt (P15121)
Pfam (PF00248)
In PDB
Homo sapiens (human)AR, Aldehyde reductase
2ANADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3A2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDEnon-polymer335.33Chemie (ITB)
4waterwater18.0214Chemie (HOH)
Sequence modifications
A: 0 - 315 (UniProt: P15121)
PDBExternal DatabaseDetails
Ile 4Leu 4SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35898.3
Non-Polymers*Number of molecules4
Total formula weight1749.3
All*Total formula weight37647.6
*Water molecules are not included.

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PDB entries from 2024-09-11

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