2NTI
Crystal structure of PCNA123 heterotrimer.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (D, A, G) | DNA polymerase sliding clamp B | polymer | 249 | 27521.7 | 3 | UniProt (P57766) Pfam (PF00705) | Sulfolobus solfataricus | Proliferating cell nuclear antigen homolog B, PCNA B |
| 2 | B, E, H (E, B, H) | DNA polymerase sliding clamp C | polymer | 246 | 27592.3 | 3 | UniProt (Q97Z84) Pfam (PF00705) Pfam (PF02747) | Sulfolobus solfataricus | Proliferating cell nuclear antigen homolog C, PCNA C |
| 3 | C, F, I (F, C, I) | DNA polymerase sliding clamp A | polymer | 244 | 27489.1 | 3 | UniProt (P57765) Pfam (PF00705) Pfam (PF02747) | Sulfolobus solfataricus | Proliferating cell nuclear antigen homolog A, PCNA A |
| 4 | AA, AB, BA, BB, CA... (F, H, A, I, D...) | BROMIDE ION | non-polymer | 79.9 | 54 | Chemie (BR) | |||
| 5 | FB (H) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 6 | GB (H) | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL | non-polymer | 384.5 | 1 | Chemie (7PG) | |||
| 7 | NB, OB, PB, QB, RB... (D, E, F, A, B...) | water | water | 18.0 | 1046 | Chemie (HOH) |
Sequence modifications
D, A, G: 1 - 249 (UniProt: P57766)
E, B, H: 2 - 246 (UniProt: Q97Z84)
| PDB | External Database | Details |
|---|---|---|
| Val 2 | Phe 2 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 247809.3 | |
| Non-Polymers* | Number of molecules | 56 |
| Total formula weight | 4738.4 | |
| All* | Total formula weight | 252547.7 |
