2NQA
Catalytic Domain of Human Calpain 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Calpain-8 | polymer | 326 | 36680.0 | 2 | UniProt (A6NHC0) Pfam (PF00648) UniProt (by SIFTS) (P17655) | Homo sapiens (Human) | New calpain 2,nCL-2,Stomach-specific M-type calpain |
| 2 | C, D (D, E) | Leupeptin Inhibitor | polymer | 4 | 429.6 | 2 | BIRD (PRD_000216) | Actinomycetes Streptomyces roseus MA 839-A1 | |
| 3 | E, F, G, H, I (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | J, K, L, M (A, B, D, E) | water | water | 18.0 | 308 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 346 (UniProt: A6NHC0)
| PDB | External Database | Details |
|---|---|---|
| Gly 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Tyr 245 | Ser 245 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 74219.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 200.4 | |
| All* | Total formula weight | 74419.6 |
